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Why was Januvia taken off the market?

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Why was Januvia taken off the market?

Lawsuit documents reveal that doctors prescribed Januvia to the husband in 2007 to control his Type II diabetes symptoms to enjoy his day-to-day existence. He stopped taking the medication in October 2010 after learning he had been diagnosed with pancreatic cancer.

Has anyone died from taking Januvia?

Researchers found a small increase in pancreatic risk and said pancreatitis and pancreatic cancer were “uncommon” in people taking the drug. Out of 7,332 people who took sitagliptin, 23 developed acute pancreatitis. Four of those cases were severe, and two of the patients died.

Which is safer metformin or Januvia?

Summary. Januvia and metformin are both effective drugs that are used to help manage blood sugar levels in patients with type 2 diabetes. Although both drugs can cause serious side effects, there are fewer side effects associated with Januvia and the drug is better tolerated than metformin.

When should you not take Januvia?

Who should not take JANUVIA?

  1. low blood sugar.
  2. acute inflammation of the pancreas.
  3. chronic inflammation of the pancreas.
  4. chronic kidney disease stage 3B (moderate)
  5. chronic kidney disease stage 4 (severe)
  6. chronic kidney disease stage 5 (failure)
  7. kidney disease with likely reduction in kidney function.

Is there a lawsuit against Januvia?

Judges consolidated lawsuits against the makers of Type 2 diabetes drugs Januvia, Janumet, Byetta and Victoza in California federal court. Nearly 1,000 plaintiffs claim the drugs caused pancreatic cancer and pancreatitis.

What are the side effects of Januvia 50 mg?

The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with metformin and rosiglitazone (Avandia ®).

Can you stop taking Januvia cold turkey?

Don’t stop taking Januvia unless recommended by your doctor. If you stop taking it, your blood sugar levels will go back up.

What is a good substitute for Januvia?

Alternatives to Januvia

  • linagliptin (Tradjenta)
  • metformin (Glucophage, Glucophage XR, Fortamet, Glumetza)
  • empagliflozin (Jardiance)
  • canagliflozin (Invokana)
  • saxagliptin (Onglyza)
  • alogliptin (Nesina)
  • glipizide (Glucotrol and Glucotrol XL)
  • sitagliptin and metformin hydrochloride (Janumet)

Should I take metformin and Januvia at the same time?

Because metformin and Januvia often pair together, there are not many negative interactions between the two drugs. Each drug has its separate side effects, and new users should contact their physician if any of the symptoms below arise.

Is Januvia bad for the liver?

Now, a new medical journal “To The Editor” letter suggests that Januvia may have a negative effect on the liver for certain patients, specifically “individuals with a history of nonalcoholic steatohepatitis or elevated hepatic enzymes”.

Is Januvia bad for the kidneys?

Januvia (sitagliptin) can now be used at a lower dose in patients with moderate to severe renal impairment.

How many lawsuits are against Januvia?

The lawsuits landed in courts across the country and claimed the drugmakers failed to warn about the risk. Nearly 950 lawsuits over Januvia, Janumet, Byetta and Victoza are pending in a federal court in California.

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